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Notably, there was no difference in the TNF protein expression of between BRCA and normal tissues in TCGA database, which possibly due to the abnormal expression of TNF in physiological or pathological states such as the inflammatory response and immune regulation 47

Recently, a study highlighted that overexpressing MT-3 reduces ROS levels in early adipocyte differentiation, while antimycin A treatment restores ROS levels

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Circulation 134 , 883894 (2016)

When not bound to G-actin, it translocates to the nucleus, where it regulates gene expression on association with serum response factor