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This is caused by things like physical stress, mental stress, NSAIDs, alcohol, pesticides and many other contributing factors

Eur J Pharm Biopharm

Es interesante en enfermos crnicos, que padecen problemas respiratorios, digestivos, hepticos o metablicos como la diabetes

In particular, the interplay of diabetes, CKD, and HF has received increasing attention in recent years [9], also spurred by emerging therapies that improve the outcome of all three of these entities

The authors suggest a potential role of nitric oxide in promoting these findings, as nitric oxide is a signaling molecule known to facilitate vasodilatation by acting on vascular smooth muscle cells [30]