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After particle picking and two-dimensional classification, several classes were produced with gB in the prefusion state, resembling our stabilized HSV-1 gB structure, in addition to classes showing the easily identifiable postfusion conformation in side and top views

[DOI] [PMC free article] [PubMed] [Google Scholar] 227.Kilpatrick BS et al

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Know what you are dealing with before choosing a treatment approach