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Six weeks of treatment with AlCl 3 caused nitrosative oxide stress (lipid peroxidation), cognitive impairment, an increase in proinflammatory cytokines (IL-1beta and TNF-alpha) and increased AChE activity and reduced the BDNF content in the hippocampus of animals

Pirfenidone attenuates nonalcoholic fatty liver disease through activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway