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36 As discussed below, one of the most important future goals will be to assess whether all forms of externalized PS are immunosuppressive

The outer carboxymethyl cellulose shell functions as a cellulase-degradable gate that restricts premature diffusion

Understanding the intrinsic cellular mechanisms and external environmental factors that affect the stability of Tregs across different diseases can facilitate the development of more precise Treg-targeted immunotherapies with significant clinical value

found that (110), AD can reduce the production of anti-CII, TNF, IL-1 and IL-6 in the serum of CIA mice, and can also decrease the phosphorylation of p38 MAPK and ERK1/2 in RASFs induced by TNF in a dose-dependent manner