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Patients with early Leber's disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

1a, normal SD rats were placed in open field boxes to compare baseline and peptide-induced locomotor activities among the three treatment groups ( n = 68 animals per group)

[13] In a newly diagnosed vitamin B 12 -deficient patient, normally defined as when serum levels are less than 200 pg/ml, daily IM injections of hydroxocobalamin up to 1,000 g (1 mg) per day are given to replenish the body's depleted cobalamin stores

The formation of red blood cells requires B12