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M.LeanI

Nat Commun 9:3294 Wang G, Fan Y, Zhang G, Cai S, Ma Y, Yang L, Wang Y, Yu H, Qiao S, Zeng X (2024) Microbiota-derived indoles alleviate intestinal inflammation and modulate microbiome by microbial cross-feeding

The formation of gamma-glutamylcysteine is the rate-limiting reaction in GSH synthesis and is feedback inhibited by GSH itself, a mechanism responsible for the regulation of cellular GSH concentration