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In the eye of the storm: immune-mediated toxicities associated with CAR-T cell therapy

107,109 A significant consequence of OXPHOS dysfunction is the increased production of mtROS due to decreased electron transfer efficiency in the ETC, which results in more electrons leaking and interacting with O 2

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4.2 Integration with existing literature and study design rationale Although grounded in the Philippine context, these findings may also be relevant to other postcolonial societies in Southeast Asia, Africa, and Latin America, where colonial histories, class hierarchies, and globalized beauty ideals similarly shape skin tone preferences and appearance-related distress