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Description

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Lipid rafts: Buffers of cell membrane physical properties

First, the bioavailability and hepatic delivery of many dietary antioxidants (e.g., polyphenols, vitamins C and E) are often low and highly variable between individuals

Polishchuk, A

Lipid peroxidation disrupts cell membranes, protein oxidation leads to loss of function and structural integrity, and DNA damage can cause mutations and genomic instability [9]