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5 Clinical relevance of ammonia death 5.1 Targeting glutamine metabolism-related pathways Based on current research progress, anti-tumor strategies targeting glutamine metabolism have established a multi-level intervention system, primarily encompassing three major directions: transport inhibition, key enzyme blockade, and combination therapies

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80,97,98,99,100,101 A detailed history taking identifies symptoms related to sensory, motor, and autonomic dysfunction, while a physical examination focuses on sensory and motor deficits, and reflex abnormalities

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