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108 Also, neoalbaconol inhibited the activity of key energy metabolic enzyme hexokinase 2 (HK2), which eventually resulted in a striking energy crisis

We then used the model to study different dosing strategies and found that modest differences result from different dosing strategies as long as they are started early enough (Figure12)

Abstract Background Discrepancies in the utilization of reactive oxygen species (ROS) between cancer cells and their normal counterparts constitute a pivotal juncture for the precise treatment of cancer, delineating a noteworthy trajectory in the field of targeted therapies

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Cant C, Auwerx J