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The gut microbiota is correlated with intestinal motility, with the enrichment of certain microbes, such as Rumioncoccaceae, Eubacterium, Butyricimonas , and Bacteroidetes , during constipation and the depletion of Prevotella, Faecalibacterium , and Dialister during diarrhea [293, 294]

However, as the pathogenesis of AD is complex (it is derived from both genetic and epigenetic factors), mechanisms of action of AGE on the improvement of cognitive and memory loss are also very complex

21872010, L.F.), and the Fundamental Research Funds for the Central Universities (2233300007, Y.Z.)

Blood 140 , 630643 (2022)

[31] found that GH and IGF-1 have distinct, yet overlapping, functions during mammalian linear growth