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Tirzepatide is the older, fully matured story: a single-molecule dual incretin agonist taken from discovery through Phase 1 proof-of-concept, [7] then through the large SURPASS (diabetes) and SURMOUNT (obesity) Phase 3 programs, and finally to FDA and EMA approval

The main benefits I've noticed are a significant reduction in fatigue especially that post-Tirzepatide slump and a noticeable boost in my body's ability to burn fat

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Since the COVID-19 vaccines cause immunization against SARS-CoV-2 infection spike proteins, which bind to gangliosides and glycoproteins on cell surfaces, the causal connection could be the cross-reaction between antibodies produced by COVID-19 vaccines and GBS (212)