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Oral administration of l-carnitine (3 g/d) with omega-3 fatty acids could increase carnitine palmitoyl-transferase-I activity and relieve clinical symptoms of CFS 642

A recent phase II clinical trial in Parkinsons disease, which assessed DFP in 372 newly diagnosed, untreated PD patients over 36 weeks, revealed that DFP not only failed to improve disease symptoms but was associated with a worsening of motor and non-motor symptoms compared to placebo (Devos et al., 2022)