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In addition, multiple signs of nerve damage were observed, including irregular distribution and variable thickness of myelin sheath, degeneration of fibers, axonal disintegration, and notable edema of the nerve fibers

We describe how, in mammals, the redox-active nature of iron is managed at the cellular level, particularly regulation by iron-response proteins (IRPs), and discuss how intracellular iron regulates IRPs

Efficacy and Safety of Lesinurad in Patients with Hyperuricemia Associated with Gout: A Systematic Review and Meta-Analysis of Randomized Controlled Trials