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Enhancing model accuracy with humanized mice or advanced imaging can improve clinical applicability

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There are several mechanisms for hepatotoxicity relating to antiretroviral agents: hypersensitivity hepatitis (nevirapine or NVP), mitochondrial toxicity and hepatic steatosis (d4T, ZDV, ddI), direct hepatotoxicity (Protease inhibitors or PIs) and immune reconstitution in HCV or HBV co-infected patients

Evid-Based Complementary Alternat Med 2012:163106 Zhao X, Li R, Jin H, Jin H, Wang Y, Zhang W, Wang H, Chen W (2018) Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways

In those facility settings, the injection administration is considered part of the facilitys APC payment, and a physician billing 96372 on top of a facility billing for the same service creates a duplicate payment issue