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Furthermore, through a small molecule screen, a novel METTL14 inhibitor named WKYMVM, which can restore sensitivity to CDK4/6i in CDK4/6i-resistant breast cancer cells, was identified

In the second reaction, glycine is attached to the C-terminal of -EC and this reaction is catalyzed by glutathione synthase (GSH2, EC 6.3.2.3) forming the tripeptide reduced glutathione (GSH) (Meister 1988) (Figure 4.1)

Avoid food 2 hours before and 45 minutes after injection

10.1016/j.ejps.2017.10.024 75 SanoM.IchiharaG.KatsumataY.HiraideT.HiraiA.MomoiM

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