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Filaggrin plays a crucial role in lipid synthesis within the stratum corneum of the skin, whereas keratin is essential for the formation of the skin barrier

In a mouse model of neuroinflammation, magnesium L-threonate injection into the brain cavity inhibited neuroinflammation by suppressing IL-1 expression (Wang 2017)

The activation of SREBP by mTORC1 also increases flux through the pentose phosphate pathway, leading to the production of NADPH and other intermediate metabolites necessary for cellular proliferation and growth