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doi:10.1111/j.1460-9568.2011.07707.x 91

The CD38 hydrolase activity is largely responsible for the conversion of NAD + to ADO within the hypoxic, acidic MM niche [25]

At the cellular level, the permeability of membranes for succinate is limited by its charged nature necessitating cellular transporters for its transfer

One-way ANOVA showed significant differences between the groups in terms of age ( p = 0.001), hence age was included as a covariate in between group comparisons of metabolite concentrations