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Neuroinflammation in ME/CFS was initially suggested by studies showing elevated levels of pro-inflammatory cytokines, and decreased anti-inflammatory cytokines, in cerebrospinal fluid from lumbar punctures in ME/CFS patients [62, 63], and further supported by a positron emission tomography (PET) study [64], which showed increased binding of a radioligand to 18 kDa translocator protein (TSPO) receptor, the expression of which increases when microglia are activated

The Mesopeel treatment can be combined with other anti-aging treatments such as Mesotherapy, Botox, Vbeam and various Skin tightening lasers to achieve pan-facial rejuvenation

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2 Current management of NTHi infections necessitates alternative therapeutic strategies 2.1 Antibiotic therapy NTHi-associated lower respiratory infections are typically treated with moderate spectrum -lactam (typically amoxicillin or amoxicillin-clavulanic acid) antibiotics (Marchant et al., 2024)