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It may achieve this by upregulating vascular endothelial growth factor (VEGF), an endogenous protein responsible for stimulating the growth of new blood vessels [4]

10.1080/09168451.2014.930320 119 MaahsD

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33 identified that the gut microbe-derived metabolite trimethylamine N-oxide enhanced immunotherapy sensitivity, associated with an immunostimulatory tumor-associated macrophage and activated effector T cell response in the tumor microenvironment