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Ananda S, Nowak AK, Cher L, Dowling A, Brown C, Simes J, et al

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Metabolic Monitoring Protocols: What Should Happen Based on current evidence and clinical guidelines, heres what metabolic monitoring should look like for patients on antidepressants: Baseline Assessment (Before Starting or Changing Antidepressant) Measurements: Height and weight calculate BMI Waist circumference Blood pressure Laboratory tests: Fasting glucose OR hemoglobin A1c Lipid panel (total cholesterol, LDL, HDL, triglycerides) Risk assessment: Personal history of obesity, diabetes, metabolic syndrome Family history of diabetes, cardiovascular disease Current weight and metabolic status History of weight gain on previous psychiatric medications This baseline allows tracking of changes attributable to medication

Individuals with inflammatory bowel disease, gastroparesis, or other gastrointestinal disorders require special consideration for tirzepatide dosing for weight loss in units