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Avoid in Certain Populations: Contraindicated in active peptic ulcer disease, recent gastrointestinal bleeding, or perforation, advanced renal impairment, and concurrent use with other NSAIDs or aspirin

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One of the key strategies for addressing oxidative stress is to lower the reactive oxygen species creation in the mitochondrion which is one of the main sites of their generation by using antioxidants, where they prevent oxidants from transferring electrons to other molecules

The ratio of Tween 80/Span 20 was varied as 1:1, 1:2, 2:1, 3:1, and 3:2

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