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While several researchers have endeavored to pinpoint the exact mechanisms of action based on experimental findings, a comprehensive understanding of the stepwise pathways and the full scope of essential oils potential necessitates further in-depth research

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The synthetic SeAM analogue ProSeAM appears to be processed by G9a/EHMT2 and SUV39H2 when evaluated using purified HMTs in a cell-free system and in cancer cell lines, suggesting that SeAM could be used as an HMT substrate [64]