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Research co-design in health: a rapid overview of reviews

The efficacy of treatments of comorbid pain and depression has been less studied, but it is well known that these two conditions worsen each others severity and therapeutic response

Basic scientific investigation effort should be geared toward elucidating the biologic mechanisms of PD

22,56,57 Cardiovascular diseases and related risk factors (e.g., hypertension, atherosclerosis) impair blood flow to peripheral nerves, worsening neuropathic symptoms