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34 The cytosolic RNA-sensing pathway was initially identified as a key part of host immune surveillance against RNA virus infection

10.1111/ics.12728 117

10.1056/nejm199906173402418 103 WenzelS

The reaction mixture contained 1 mL reagent A, 40 L enzyme extract and 10 L reagent B

Early nanoformulations, such as liposomes and polymeric micelles, were primarily designed to improve solubility and pharmacokinetics and to exploit enhanced vascular permeability and impaired lymphatic drainage for passive tumor accumulation [18, 20, 21]