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TRAF6 itself can trimerize through its TRAF domains and further dimerize through its N-terminal RING and Zn finger domains, both together resulting in higher-order oligomerization of TRAF6 46,68

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Carriazo Ruiz, Jos Ramn, and Maria Jess Mancho Duque

While Cbl plays a crucial role in modulating redox homeostasis, its deficiency has been linked to oxidative stress and various neurological manifestations