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The organic extract was dried at room temperature under a gentle stream of nitrogen and 250 L running buffer (50:50 methanol:dichloromethane, MeOH:DCM with 10 mM ammonium acetate) were added to the dried samples

Methods A non-systematic literature search was performed on PubMed using as search terms (acetyl-l-carnitine OR L-acetylcarnitine OR ALCAR) in conjunction with one of the following: nerve damage, neuropathy, peripheral neuropathy, radiculopathy, neuropathic pain, diabetic polyneuropathy, chemotherapy-induced polyneuropathy, carpal tunnel syndrome, Fabry disease