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For most HCC patients, the high-capacity plasmid used by GNOS-PV02 is sufficient to cover neoantigens in the tumor, allowing the immune system to select the most effective neoantigens on its own

Martemucci G, Costagliola C, Mariano M, Dandrea L, Napolitano P, DAlessandro AG

For transient transfection paradigms, 4 to 15 g of cDNA coding for N -terminally Flag-tagged WT human parkin or empty Flag control vector (pcDNA3.1) using a 1:1 ratio of cDNA:Lipofectamine 2000, was used for ectopic expression

Resveratrol-induced SIRT1 activation promotes neuronal differentiation of human bone marrow mesenchymal stem cells