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cholesterol levels in the NNMT inhibitor-treated DIO mice were similar to cholesterol levels reported by the vendor for age-matched normal chow-fed C57Bl/6 mice (www.jax.org/jax-mice-and-services/find-and-order-jax-mice/most-popular-jax-mice-strains/dio-b6)

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Mice that dont easily gain weight have less NNMT

For women with known PCOS or other reproductive endocrine conditions, baseline and follow-up assessments of metabolic and reproductive parameters can help distinguish medication effects from underlying disease progression