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In the quest for optimal fitness and health, timing is everything, especially when it comes to L-carnitine

Genetic sequencing is not solely a research tool for CVS but is employed on a daily basis by the Corresponding Author in the clinical management of the condition in his patients, generally involving WGS as it also includes useful information in the mtDNA sequence, genetic architecture (large rearrangements), and pharmacogenomic variants (e.g., in dosing amitriptyline)

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Patients with secondary carnitine deficiency accumulate organic acids which causes enhanced urinary excretion of carnitine in the form of acyl-carnitines [36, 37]

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