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In Erastin-induced ferroptosis, the expression of lysosome-associated membrane protein 2a (LAMP2a) is increased, which promotes heat shock protein 90 (HSP90)-dependent autophagy, which in turn mediates the degradation of GPX4[67]

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fasciculare ) 3,5-D showed no reduction in all transformants, indicating the involvement of a different type of key enzyme in its biological synthesis (Supplementary Figure 32 and Table 4)

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