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Collectively, these findings indicate that the ferroptotic fate of CRC cells is determined by a dynamic interplay between intrinsic oncogenic signals and opposing 'pro-death' and 'anti-death' metabolites derived from the gut microenvironment

Funding This work was financially supported from Continuous Flow Engineering Laboratory of the National Petroleum and Chemical Industry of School of Pharmacy, Changzhou University and Jiangsu BioScene Pharma

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