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AICAR is itself a potent AMPK activator, the same intermediate compound that the pharmaceutical agent AICAR infusion uses to mimic exercise in rodent studies

PKC- was required for morphine-induced MOR desensitization but not upon etorphine, fentanyl and DAMGO (Zheng et al., 2011)

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Quick Reference: Standard Protocol Community-documented protocol: 1 mg subcutaneous in the morning, 5 days on / 2 days off, for 2-week courses repeated 2-3 times per year, with 3-6 months rest between courses