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In preclinical research settings, experimental models may examine its role in pathways associated with oxidative stress regulation, detoxification mechanisms, and cellular response systems

Vitamin C and its derivatives inhibit tyrosinase activity and melanin content in a dose-dependent manner [86]

Therefore, to more clearly reflect the effect of IS on plasma GSH homeostasis, it was more appropriate to use as a comparison group not healthy people characterized by a normal balance of thiols, but people at risk of stroke, which include patients with cerebral microangiopathy

MCOLN1/ cells show obvious Fe 2+ deposition in lysosomes and cause cellular iron metabolism disorder and neuronal degeneration (Dong et al., 2008)

[DOI] [PubMed] [Google Scholar] 123.Mitchell J.P., Carmody R.J