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Reductive carboxylation epigenetically instructs T cell differentiation

Further, a new RNA-guided CRISPR activation (CRISPR-Act3.0) system has been introduced in plants for simultaneous editing of multiple genes based on the deactivated Streptococcus pyogenes Cas9 (dSpCas9) and demonstrated in tomato (Pan et al., 2021)

These findings contrast with our observations in a previous study in the DBA/2 J mouse model of glaucoma, where we observed that the ketogenic diet afforded neuroprotection of RGCs concomitant with PGC-1 upregulation (Harun-Or-Rashid et al., 2018)