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SKU: 30663948906
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Description

Cullin-5 controls the number of megakaryocyte-committed stem cells to prevent thrombocytosis in mice

Since germline deletion of Grk2 is lethal, Grk2 hemizygous mice (GRK2 +/ ), shRNA-GRK2 transgenic mice, or knockdown in local organs have been used to investigate its effects on the regulation of blood pressure