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After 72 h treatments, 0.5 g ml 1 propidium iodide (Sigma-Aldrich, P4864) and 1.4 g ml 1 Hoechst 33342 (Invitrogen, H3570) were added to cells

Hepatic transcriptome analysis identifies 1,503 differentially expressed genes, 601 of which differ in both early and late disease stages, involving significant dysregulation of oxidative stress and lipid metabolic pathways

Pre-existing vulnerability : People with type 2 diabetes have higher rates of anxiety and depression compared to the general population, which may make them more susceptible to panic symptoms regardless of medication

The absorbance at 450 nm was measured via a microplate reader (Thermo Fisher, USA)

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