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For example, FAD-free NQO1 or a cancer-associated P187S mutant form of NQO1 exhibits reduced FAD binding and is degraded by the ubiquitinproteasome system 53,60

J Pediatr 138(Suppl):S46S55 Arbeiter AK, Kranz B, Wingen Bonzel KE, Dohna AM, -Schwake C, Hanssler L, Neudorf U, Hoyer PF, Bscher R (2010) ontinuous venovenous haemodialysis (CVVHD) and continuous peritoneal dialysis (CPD) in the acute management of 21 children with inborn errors of metabolism

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However, we did not observe any amelioration of motor impairment in PARK2 knockout mice exposed to rotenone, although cognitive impairment was attenuated by etomoxir treatment (Fig