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Future translational efforts should pursue several directions: first, conducting deep-phenotyping trials in biopsy-confirmed MASH patients, using positron emission tomography to quantify hepatic glucose uptake and correlating these findings with intrahepatic insulin signaling (e.g., p-AKT)

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16 The aim of this paper is to review the evidence for the use of B12 in clinical practice beyond the replacement in deficiency

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