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Consequently, FerroTACs exhibit enhanced cellular accumulation and potent degradation activity, outperforming conventional PROTACs in certain models and offering a strategic insight into designing degraders with improved pharmacokinetic profiles

All these data show that connections between the expression of MDR proteins and the outcome of a tumor therapy are not very simple

Discussion The physiological agent(s) responsible for reducing PADs to their physiologically active state have not been identified