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During this process, tumor cells undergo a transformation from an epithelial phenotype to a more aggressive mesenchymal phenotype, enhancing the ability to evade the effects of the drug and promote survival

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Singh N, Gurav A, Sivaprakasam S, Brady E, Padia R, Shi H, Thangaraju M, Prasad PD, Manicassamy S, Munn DH, Lee JR, Offermanns S, Ganapathy V (2014) Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

Gul S, Gribbon P (2010) Exemplification of the challenges associated with utilising fluorescence intensity based assays in discovery