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In the urethane-induced lung carcinogenic model, emodin reduces hypercoagulation and tumor lesions, accompanied by a decrease in N2 neutrophils and modulated cytokine profiles (IFN- , IL-12 up

This is accomplished through tightly regulated uptake and efflux and through the expression of metal-binding proteins, such as metallothioneins, that effectively sequester pools of zinc and copper

Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts

Topical applications provide another avenue for treatment, allowing direct scalp application and easy incorporation into existing hair care routines

from National Health Research Institutes, Taiwan (NHRI-EX111-10703PI)