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The transport capability of MSNs at the sizes of 20, 40, and 80 nm were evaluated by the authors and were calculated to be 44.0%, 59.2%, and 38.6%, respectively, which were all higher than that of free drugs (32.8%), indicating a size-dependent penetration mechanism

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As we learned in part 5, intestinal permeability is now being theorized to be one of the primary mechanisms in the pathogenesis (development of disease) of autoimmune disease

Instead, a significant portion of the enzymes can be absorbed intact through the intestinal wall and into the bloodstream