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Table 4: Changes from Week 26 Baseline to Week 52 in Visceral Adipose Tissue (cm 2 ) by Treatment Group (Intent-To-Treat Population with Last Observation Carried Forward) Figure 2 shows the percent change in VAT from baseline (Week 0) over time until 52 weeks in completer patients

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In a subset of ASDs, such as the syndromic ASD fragile X syndrome, Rett syndrome (RTT) and tuberous sclerosis, mutations of genes have been found to be related to synaptic function, suggesting that abnormal neuronal homeostasis is a risk factor for ASD (Auerbach et al., 2011

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That these studies did not report on the daytime zenith of IL6 at about 19.0020.00 h could be attributable to their using infrequent sampling or a small number of subjects