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While beneficial for normal growth, it poses a theoretical risk of accelerating the growth of existing or dormant cancers (for example, prostate, breast, colon) by inhibiting apoptosis (programmed cell death) and driving cell replication

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Gurbet A, Bekar A, Bilgin H, Korfali G, Yilmazlar S, Tercan M

In a clinical study, researchers evaluated cDC1 vaccine pulsed with HER-2 peptide in early invasive breast cancer (IBC) and ductal carcinoma in situ (DCIS) ( in vitro and induced a long-lasting Th1 response in 27 patients with DCIS who overexpressed HER-2 (Sharma et al., 2012