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263 These two studies suggest that canakinumab treatment may have therapeutic potentials in non-ICU patients with mild or severe COVID-19

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review Cancer Res 1989 49 : 64496465 Tannock IF, Rotin D

Morshedzadeh N, Shahrokh S, Aghdaei HA, Amin Pourhoseingholi M, Chaleshi V, Hekmatdoost A

Given that COVID-19 infection can cause oxidative damage in various organs and tissues, SARS-CoV-2 infection can cross the cell membrane via the angiotensin 1 converting enzyme 2 (ACE2) receptor

However, like any substance, it should be used with caution