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Following IVM, oocyte maturation was scored, with GV oocytes being identified by the presence of a nuclear envelope and nucleolus, MI oocytes identified by the absence of the nuclear envelope and nucleolus, MII oocytes identified via the presence of the first polar body, and degenerative oocytes identified via cytoplasmic fragmentation 106, 107

What is the GCN2 pathway

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They are not considered defects, but rather differences in the genetic code, much like having blue eyes instead of brown

Int J Infect Dis (2021) 111:21926