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GHK-Cu combines the tripeptide glycyl-l-histidyl-lysine (GHK) and copper (Cu)

The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]

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Cell Division Orientation Is Coupled to Cell-Cell Adhesion by the E-Cadherin/LGN Complex. Nature Communications 8 (2017): n