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In this simplified view of the immune system, antigen-presenting cells phagocytose antigens and present them to T cells, thereby activating the T cells

D., Wise, R

10.1038/s41419-019-1678-y 55 UtamaG

In contrast to previously identified cyclin-Cdk docking motifs, which are short linear motifs in intrinsically disordered regions of proteins, Rb helix-based docking is unique in its structural requirement

412,413 For example, in a mouse model of lung adenocarcinoma, the delivery of PNAs targeting CEACAM6 using pHLIPs resulted in CEACAM6 gene silencing and tumor growth inhibition